(19)

(11)

EP 2 244 753 A2

(12)

(43) Date of publication: 03.11.2010 Bulletin 2010/44 (21) Application number: 09710810.4 (22) Date of filing: 12.02.2009

(51) International Patent Classification (IPC):  A61L 27/20(2006.01) A61L 27/52(2006.01) A61L 27/38(2006.01) (86) International application number: PCT/IB2009/000258 (87) International publication number: WO 2009/101518 (20.08.2009 Gazette 2009/34)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA RS (30) Priority: 15.02.2008 PT 10397008 (71) Applicant: Associacion for the Advancement of Tissue Engineering and Cell Based Technologies & Therapies (A4TEC) 4710-057 Braga (PT)	(72) Inventors: OLIVEIRA, João Teixeira de P-4450-282 Matosinhos (PT) SOUSA, Rui Amandi de P-4450-204 Matosinhos (PT) REIS, Rui Luís P-4250-242 Porto (PT) (74) Representative: Magalhaes Simoes, José Raul  Simoes, Garcia, Corte-Real & Associados - Consultores, Lda. Av. Estados Unidos de América, No 131,7o-C 1700-173 Lisboa 1700-173 Lisboa (PT)