(19)

(11)

EP 2 245 067 A2

(12)

(88) Date of publication A3: 17.06.2010 (43) Date of publication: 03.11.2010 Bulletin 2010/44 (21) Application number: 09711479.7 (22) Date of filing: 09.02.2009

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) A61P 37/06(2006.01) A61P 13/12(2006.01) (86) International application number: PCT/EP2009/051467 (87) International publication number: WO 2009/101059 (20.08.2009 Gazette 2009/34)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA RS (30) Priority: 11.02.2008 US 65381 (71) Applicant: Novartis AG 4056 Basel (CH)	(72) Inventor: SAINT-MEZARD, Pierre 4002 Basel (CH) (74) Representative: Kassow, Anders  Novartis Pharma AG Patent Department 4002 Basel 4002 Basel (CH)