FUSED HETEROARYL MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-KB ACTIVITY AND USE THEREOF - Patent 2247597

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EP 2 247 597 A1

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(43)	Date of publication:
	10.11.2010 Bulletin 2010/45

(21)	Application number: 09708143.4

(22)	Date of filing: 05.02.2009

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International Patent Classification (IPC):

C07D 491/04^(2006.01)
A61P 29/00^(2006.01)
A61K 31/436^(2006.01)

A61P 3/00^(2006.01)
A61P 37/00^(2006.01)
C07D 491/147^(2006.01)

(86)	International application number:
	PCT/US2009/033134

(87)	International publication number:
	WO 2009/100171 (13.08.2009 Gazette 2009/33)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
	Designated Extension States:
	AL BA RS

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Priority:

07.02.2008 US 26816

(71)	Applicant: Bristol-Myers Squibb Company
	Princeton, NJ 05843-4000 (US)

(72)	Inventors:
	DUAN, Jingwu Princeton, New Jersey 08543 (US) WEINSTEIN, David, S. Princeton, New Jersey 08543 (US) JIANG, Bin Princeton, New Jersey 08543 (US)

(74)	Representative: Beacham, Annabel Rose
	Dehns St Bride's House 10 Salisbury Square London EC4Y 8JD London EC4Y 8JD (GB)

(54)	FUSED HETEROARYL MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-KB ACTIVITY AND USE THEREOF