(19)

(11)

EP 2 252 218 A2

(12)

(88) Date of publication A3: 12.11.2009 (43) Date of publication: 24.11.2010 Bulletin 2010/47 (21) Application number: 09710690.0 (22) Date of filing: 11.02.2009

(51) International Patent Classification (IPC):  A61B 17/068(2006.01) A61B 17/04(2006.01) (86) International application number: PCT/US2009/033777 (87) International publication number: WO 2009/102776 (20.08.2009 Gazette 2009/34)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA RS (30) Priority: 11.02.2008 US 27522 P (71) Applicant: CeloNova Biosciences, Inc. Peachtree City, GA 30269 (US)	(72) Inventors: FRITZ, Ulf 69434 Hirschhorn (DE) FRITZ, Olaf 69434 Hirschhorn (DE) WOJCIK, Ronald Canton, GA 30114 (US) GASKINS, Ralph, E. Atlanta, GA 30326 (US) (74) Representative: Midgley, Jonathan Lee et al Scott & York Intellectual Property Ltd 45 Grosvenor Road St. Albans Hertfordshire AL1 3AW St. Albans Hertfordshire AL1 3AW (GB)