(19)

(11)

EP 2 252 629 A2

(12)

(88) Date of publication A3: 17.12.2009 (43) Date of publication: 24.11.2010 Bulletin 2010/47 (21) Application number: 09716993.2 (22) Date of filing: 27.02.2009

(51) International Patent Classification (IPC):  C07K 14/47(2006.01) A61P 31/06(2006.01) A61K 38/17(2006.01) (86) International application number: PCT/EP2009/052405 (87) International publication number: WO 2009/109532 (11.09.2009 Gazette 2009/37)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA RS (30) Priority: 07.03.2008 EP 08152499 (71) Applicant: Novozymes Adenium Biotech A/S 2880 Bagsvaerd (DK)	(72) Inventors: HOEGENHAUG, Hans-Henrik Kristensen DK-2880 Bagsvaerd (DK) SCHOOLNIK, Gary K. Palo Alto California 94303-3514 (US) CHOPRA, Sidharth Menlo Park California 94025 (US) SEGURA, Dorotea Raventos DK-2880 Bagsvaerd (DK)