(19)
(11) EP 2 263 681 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
19.08.2015 Bulletin 2015/34

(45) Mention of the grant of the patent:
17.06.2015 Bulletin 2015/25

(21) Application number: 09162954.3

(22) Date of filing: 17.06.2009
(51) International Patent Classification (IPC): 
A61K 35/22(2015.01)
A61P 35/00(2006.01)

(54)

Separation and formulation of bioactive fraction and subfraction from camel urine work as anticancer agent

Trennung und Formulierung einer bioaktiven Fraktion und Unterfraktion aus der Kamelurinbearbeitung als Antikrebsmittel

Séparation et formulation de fraction bioactive et travail de sous-fraction d'urine de chameau en tant qu'agent anti-cancer


(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

(43) Date of publication of application:
22.12.2010 Bulletin 2010/51

(73) Proprietor: Khorshid, Fatin A.
21589 Jeddah (SA)

(72) Inventor:
  • Khorshid, Fatin A.
    21589 Jeddah (SA)

(74) Representative: Viering, Jentschura & Partner Patent- und Rechtsanwälte 
Kennedydamm 55 / Roßstrasse
40476 Düsseldorf
40476 Düsseldorf (DE)


(56) References cited: : 
US-A1- 2005 100 610
US-B1- 6 410 059
US-A1- 2005 100 621
   
  • AL-HARBI M M ET AL: "Effect of camel urine on the cytological and biochemical changes induced by cyclophosphamide in mice" JOURNAL OF ETHNOPHARMACOLOGY 19960705 IE, vol. 52, no. 3, 5 July 1996 (1996-07-05), pages 129-137, XP002552633 ISSN: 0378-8741
  • KHORSID F A ET AL: "In vitro anticancer agent I-tissue culture study of human lung cancer cells A549 II-tissue study of mice leukemia cells L1210" INTERNATIONAL JOURNAL OF CANCER RESEARCH 2006 PK, vol. 2, no. 4, 2006, pages 330-344, XP002552634 ISSN: 1811-9727 1811-9735
  • KHORSHID F: "Preclinical evaluation of PM 701 in experimental animals" INTERNATIONAL JOURNAL OF PHARMACOLOGY 2008 PK, vol. 4, no. 6, 2008, pages 443-451, XP002552635 ISSN: 1811-7775 1812-5700
  • ANONYMOUS: "Camel urine a cure for cancer" MAKTOOB BUSSINESS HEALTH, [Online] - 19 May 2009 (2009-05-19) XP002552636 Retrieved from the Internet: URL:http://business.maktoob.com/2009000000 3564/0/PrintPage.htm>
  • DATABASE WPI Week 200469 Thomson Scientific, London, GB; AN 2004-706723 XP002552639 & NZ 522 665 A (BIO GRAND CO LTD) 30 April 2004 (2004-04-30)
  • KHORSHID, FA: "Potential anticancer natural product against human lung cancer cells" TRENDS IN MEDICAL RESEARCH, vol. 4, no. 1, 1 July 2009 (2009-07-01), pages 8-15, XP008113892
  • KHORSHID, FA ET AL.,: "Cytotoxic activity of bioactive fractions from PM 701" ELECTRONIC JOURNAL OF ENVIRONMENTAL, AGRICULTURAL AND FOOD CHEMISTRY, [Online] vol. 8, no. 11, 2009, pages 1091-1098, XP002552637 ISSN: 1579-4377 Retrieved from the Internet: URL:http://ejeafche.uvigo.es/index.php?opt ion=com_docman&task=doc_view&gid=556> [retrieved on 2009-10-21]
  • RAOUF GA ET AL.,: "FT-IR spectroscopy as a tool for identification of apoptosis-induced structural changes in A549 cells treated with PM 701" INTERNATIONAL JOURNAL OF OF NANO BIOMATERIALS (ARTICLE ABSTRACT), [Online] 2009, XP002552638 Retrieved from the Internet: URL:http://www.inderscience.com/search/ind ex.php?action=record&rec_id=27736&prevQuer y=&ps=10&m=or> [retrieved on 2009-10-21]
  • MURA U ET AL: "PURINE SALVAGE AS METABOLITE AND ENERGY SAVING MECHANISM IN CAMELUS-DROMEDARIUS THE RECOVERY OF GUANINE", COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B, vol. 87, no. 1, 1987, pages 157-160, XP025794571, ISSN: 0305-0491
  • MUSUMECI M L ET AL: "Use of a topic containing urea with keratolytic activity in psoriasis", DERMATOLOGIA CLINICA, CENTRO ITALIANO CONGRESSI, ROME, IT, vol. 24, no. 1-2, 1 January 2004 (2004-01-01), pages 16-18, XP009152085, ISSN: 0392-1395
  • DATABASE EMBASE [Online] ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL 1963 MARTINSON E.E. ET AL: 'The trophic effect of urea and its use in the treatment of neurotrophic skin diseases (russian)' Database accession no. EMB-0007733174 & MARTINSON E E ET AL: "The trophic effect of urea and its use in the treatment of neurotrophic skin diseases (russian)", VESTN.DERM. VENER. 1963, vol. 7, 1963, pages 2-22,
 
Remarks:
The file contains technical information submitted after the application was filed and not included in this specification
 
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).