Multi-substituted selective androgen receptor modulators and methods of use thereof

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EP 2 266 577 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	21.01.2015 Bulletin 2015/04

(45)	Mention of the grant of the patent:
	03.12.2014 Bulletin 2014/49

(21)	Application number: 10010264.9

(22)	Date of filing: 24.02.2003

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International Patent Classification (IPC):

A61K 31/655^(2006.01)
A61K 31/165^(2006.01)
C07C 331/08^(2006.01)
C07C 233/05^(2006.01)

A61K 31/275^(2006.01)
C07C 247/16^(2006.01)
C07C 255/49^(2006.01)

(54)	Multi-substituted selective androgen receptor modulators and methods of use thereof Mehrfach substituierte selektive Androgen-Rezeptor-Modulatoren und Verfahren zu ihrer Verwendung Modulateurs de récepteur sélectif d'androgène à substitutions multiples et procédé d'utilisation associés

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR

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Priority:

28.02.2002 US 453736 P
04.11.2002 US 423381 P

(43)	Date of publication of application:
	29.12.2010 Bulletin 2010/52

(62)	Application number of the earlier application in accordance with Art. 76 EPC:
	03743665.6 / 1487458

(73)	Proprietor: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
	Knoxville, TN 37996-1527 (US)

(72)	Inventors:
	Dalton, James T. Lakeland Tennessee 38002 (US) Miller, Duane D. Germantown Tennessee 38139 (US) He, Yali Florence South Carolina 25901 (US) Steiner, Mitchell S. Germantown Tennessee 38139 (US) Hwang, Dong Jin Memphis Tennessee 38134 (US) Chen, Jiyun Columbus Ohio 43210 (US)

(74)	Representative: Pearl Cohen Zedek Latzer Baratz UK LLP
	The Gridiron Building One Pancras Square London N1C 4AG London N1C 4AG (GB)

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References cited: :

WO-A-02/16310
WO-A-03/049675
US-A- 6 071 957

WO-A-98/53826
US-A- 6 019 957

DALTON J.T. ET AL.: "Discovery of nonsteroidal androgens", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., vol. 244, no. 1, 1998, pages 1-4, XP002385138, USACADEMIC PRESS INC. ORLANDO, FL.

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).