(19)

(11)

EP 2 271 644 A1

(12)

(43) Date of publication: 12.01.2011 Bulletin 2011/02 (21) Application number: 09728288.3 (22) Date of filing: 01.04.2009

(51) International Patent Classification (IPC):  C07D 413/12(2006.01) A61P 25/28(2006.01) A61P 33/06(2006.01) A61K 31/5377(2006.01) A61P 31/18(2006.01) (86) International application number: PCT/EP2009/053898 (87) International publication number: WO 2009/121914 (08.10.2009 Gazette 2009/41)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA RS (30) Priority: 02.04.2008 EP 08153929 (71) Applicant: Novartis AG 4056 Basel (CH)	(72) Inventors: HEROLD, Peter CH-4142 Münchenstein (CH) MAH, Robert CH-4132 Muttenz (CH) STUTZ, Stefan CH-4053 Basel (CH) TSCHINKE, Vincenzo CH-4102 Binningen (CH) STOJANOVIC, Aleksandar CH-4055 Basel (CH) BEHNKE, Dirk Grenzach-Wyhlen 79639 (DE) JELAKOVIC, Stjepan Freiburg 79100 (DE) (74) Representative: Carpmaels & Ransford et al One Southampton Row London WC1B 5HA London WC1B 5HA (GB)