(19)
(11) EP 2 277 047 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
17.12.2014 Bulletin 2014/51

(45) Mention of the grant of the patent:
05.11.2014 Bulletin 2014/45

(21) Application number: 09725807.3

(22) Date of filing: 27.03.2009
(51) International Patent Classification (IPC): 
G01N 33/542(2006.01)
G01N 33/58(2006.01)
 G01N 33/569(2006.01)
(86) International application number:
PCT/GB2009/050303
(87) International publication number:
WO 2009/118570 (01.10.2009 Gazette 2009/40)

(54)

Time-resolved fluorescence energy transfer (TR-FRET) assay for detecting exposure to an infectious organism

Zeitaufgelöster Fluoreszenzenergietransfer-(TR-FRET-)test zum Nachweis eines Inkontaktkommens mit einem infektiösen Organismus

Procédé de détection de l'exposition à un organisme infectieux par transfert d'énergie par résonance de type Förster en temps résolu (TR-FRET)

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

(30) Priority: 28.03.2008 GB 0805608

(43) Date of publication of application:
26.01.2011 Bulletin 2011/04

(60) Divisional application:
13161174.1 / 2618148

(73) Proprietor: The Secretary of State for Environment, Food and Rural Affairs
Addlestone Surrey KT15 3NB (GB)

(72) Inventor:
  • MCGIVEN, John
    Surrey KT15 3NB (GB)

(74) Representative: Turner, Rhiannon Rosalind et al
Greaves Brewster LLP Copa House Station Road
Cheddar, BS27 3AH
Cheddar, BS27 3AH (GB)


(56) References cited: : 
WO-A1-2005/000883
WO-A2-2008/048970
US-A1- 2006 240 571
 WO-A2-2004/041865
US-A1- 2006 234 215
   
  • QIN QIU-PING ET AL: "Time-resolved fluorescence resonance energy transfer assay for point-of-care testing of urinary albumin." CLINICAL CHEMISTRY JUL 2003, [Online] vol. 49, no. 7, July 2003 (2003-07), pages 1105-1113, XP002538503 ISSN: 0009-9147 Retrieved from the Internet: URL:http://www.clinchem.org/cgi/reprint/49 /7/1105> [retrieved on 2009-07-22]
  • GALL D ET AL: "Fluorescence polarization assay for detection of Brucella abortus antibodies in bulk tank bovine milk samples." CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY NOV 2002, [Online] vol. 9, no. 6, November 2002 (2002-11), pages 1356-1360, XP002538523 ISSN: 1071-412X Retrieved from the Internet: URL:http://cvi.asm.org/cgi/reprint/9/6/135 6> [retrieved on 2009-07-22]
  • GARIN-BASTUJI B ET AL: "The diagnosis of brucellosis in sheep and goats, old and new tools" SMALL RUMINANT RESEARCH, ELSEVIER, AMSTERDAM, NL, vol. 62, no. 1-2, 1 March 2006 (2006-03-01), pages 63-70, XP025117948 ISSN: 0921-4488 [retrieved on 2006-03-01]
  • NEWBY D T ET AL: "REAL-TIME PCR DETECTION OF BRUCELLA ABORTUS: A COMPARATIVE STUDY OFSYBR GREEN I, 5'-EXONUCLEASE, AND HYBRIDIZATION PROBE ASSAYS" APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 69, no. 8, 1 August 2003 (2003-08-01), pages 4753-4759, XP008070970 ISSN: 0099-2240
  • ANONYMOUS: "Atlas Brucella Test (Rose Bengal)" ATLAS MEDICAL, [Online] 12 June 2004 (2004-06-12), XP002538539 Retrieved from the Internet: URL:http://www.atlas-site.co.uk/index_file s/website/$8.01.00.0.0050%20Brucella%20Ros e%20Bengal%2050%20T%20S06.pdf> [retrieved on 2009-07-22]
  • HINCHLIFFE P M ET AL: "Detection of complement fixation by enzyme linked immunosorbant assay (COMPELISA)." JOURNAL OF CLINICAL PATHOLOGY JAN 1983, [Online] vol. 36, no. 1, January 1983 (1983-01), pages 100-103, XP002538540 ISSN: 0021-9746 Retrieved from the Internet: URL:http://jcp.bmj.com/cgi/reprint/36/1/10 0> [retrieved on 2009-07-22]
  • BORAKER D K ET AL: "BrucELISA: an enzyme-antibody immunoassay for detection of Brucella abortus antibodies in milk: correlation with the Brucella ring test and with shedding of viable organisms." JOURNAL OF CLINICAL MICROBIOLOGY OCT 1981, [Online] vol. 14, no. 4, October 1981 (1981-10), pages 396-403, XP002538541 ISSN: 0095-1137 Retrieved from the Internet: URL:http://www.pubmedcentral.nih.gov/picre nder.fcgi?artid=271991&blobtype=pdf> [retrieved on 2009-07-22]
  • NEWBY D T ET AL: "REAL-TIME PCR DETECTION OF BRUCELLA ABORTUS: A COMPARATIVE STUDY OFSYBR GREEN I, 5'-EXONUCLEASE, AND HYBRIDIZATION PROBE ASSAYS", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 69, no. 8, 1 August 2003 (2003-08-01) , pages 4753-4759, XP008070970, ISSN: 0099-2240, DOI: 10.1128/AEM.69.8.4753-4759.2003
  • BINZ H K ET AL: "Engineered proteins as specific binding reagents", CURRENT OPINION IN BIOTECHNOLOGY, LONDON, GB, vol. 16, no. 4, 1 August 2005 (2005-08-01) , pages 459-469, XP027676733, ISSN: 0958-1669 [retrieved on 2005-08-01]
  • NORD K ET AL: "Binding proteins selected from combinatorial libraries af an alpha-helical bacterial receptor domain", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 15, no. 8, 1 August 1997 (1997-08-01) , pages 772-777, XP002149252, ISSN: 1087-0156
  • SILVERMAN JOSHUA ET AL: "Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 23, no. 12, 20 November 2005 (2005-11-20), pages 1556-1561, XP009088629, ISSN: 1087-0156, DOI: 10.1038/NBT1166
   
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