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(11)

EP 2 278 960 A1

(12)

(43) Date of publication: 02.02.2011 Bulletin 2011/05 (21) Application number: 09721703.8 (22) Date of filing: 12.03.2009

(51) International Patent Classification (IPC):  A61K 31/00(2006.01) A61K 31/426(2006.01) (86) International application number: PCT/IB2009/051030 (87) International publication number: WO 2009/115954 (24.09.2009 Gazette 2009/39)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA RS (30) Priority: 17.03.2008 WO PCT/IB2008/050995 (71) Applicant: Actelion Pharmaceuticals Ltd. 4123 Allschwil (CH)	(72) Inventors: BROSSARD, Patrick CH-4123 Allschwil (CH) DINGEMANSE, Jasper CH-4123 Allschwil (CH) NAYLER, Oliver CH-4144 Arlesheim (CH) SCHERZ, Michael CH-4107 Ettingen (CH) STEINER, Beat CH-4143 Dornach (CH) (74) Representative: Gschwend, Thomas Peter et al Actelion Pharmaceuticals Ltd Gewerbestrasse 16 CH-4123 Allschwil CH-4123 Allschwil (CH)