(19)
(11) EP 2 281 038 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
11.06.2014 Bulletin 2014/24

(45) Mention of the grant of the patent:
23.04.2014 Bulletin 2014/17

(21) Application number: 09738244.4

(22) Date of filing: 01.05.2009
(51) International Patent Classification (IPC): 
C12N 9/96(2006.01)
(86) International application number:
PCT/EP2009/055317
(87) International publication number:
WO 2009/133200 (05.11.2009 Gazette 2009/45)

(54)

PROTEIN FORMULATION

PROTEINFORMULIERUNG

FORMULATION DE PROTÉINE


(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

(30) Priority: 01.05.2008 EP 08155538

(43) Date of publication of application:
09.02.2011 Bulletin 2011/06

(73) Proprietor: Arecor Limited
Cambridge CB4 0FE (GB)

(72) Inventor:
  • JEZEK, Jan
    Sharnbrook Bedford MK44 1LQ (GB)

(74) Representative: Teuten, Andrew John et al
Sagittarius IP Three Globeside Fieldhouse Lane
Marlow, Buckinghamshire SL7 1HZ
Marlow, Buckinghamshire SL7 1HZ (GB)


(56) References cited: : 
WO-A-2007/109221
WO-A1-01/03727
   
  • SMITH A T ET AL: "EXPRESSION OF A SYNTHETIC GENE FOR HORSERADISH PEROXIDASE C IN ESCHERICHIA COLI AND FOLDING AND ACTIVATION OF THE RECOMBINANT ENZYME WITH CA2+ AND HEME" JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,; US, vol. 265, no. 22, 5 August 1990 (1990-08-05), pages 13335-13343, XP000801340 ISSN: 0021-9258
  • JOSIC D ET AL: "PURIFICATION OF FACTOR VIII AND VON WILLEBRAND FACTOR FROM HUMAN PLASMA BY ANION-EXCHANGE CHROMATOGRAPHY" JOURNAL OF CHROMATOGRAPHY B : BIOMEDICAL APPLICATIONS, ELSEVIER SCIENCE PUBLISHERS, NL, vol. 662, no. 2, 1 January 1994 (1994-01-01), pages 181-190, XP009025613 ISSN: 0378-4347
  • GWINN ET AL: "Scalable purification of Bacillus anthracis protective antigen from Escherichia coli" PROTEIN EXPRESSION AND PURIFICATION, ACADEMIC PRESS, SAN DIEGO, CA, vol. 45, no. 1, 1 January 2006 (2006-01-01), pages 30-36, XP005198178 ISSN: 1046-5928
  • SHI XUNLONG ET AL: "Overexpression, purification and characterization of a recombinant secretary catalase from Bacillus subtilis." BIOTECHNOLOGY LETTERS JAN 2008, vol. 30, no. 1, January 2008 (2008-01), pages 181-186, XP002488448 ISSN: 0141-5492
  • WILSON COREY J ET AL: "Role of cofactors in metalloprotein folding" QUARTERLY REVIEWS OF BIOPHYSICS, vol. 37, no. 3-4, August 2004 (2004-08), pages 285-314, XP009103220 ISSN: 0033-5835
  • SEKIYA F ET AL: "REGULATION OF THE TERTIARY STRUCTURE AND FUNCTION OF COAGULATION FACTOR IX BY MAGNESIUM (II) IONS", JOURNAL OF BIOLOGICAL CHEMISTRY, THE AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, INC, US, vol. 270, no. 24, 16 June 1995 (1995-06-16), pages 14325-14331, XP002067666, ISSN: 0021-9258, DOI: 10.1074/JBC.270.24.14325
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).