(19)
(11) EP 2 282 746 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
09.12.2015 Bulletin 2015/50

(45) Mention of the grant of the patent:
28.10.2015 Bulletin 2015/44

(21) Application number: 09767153.1

(22) Date of filing: 27.03.2009
(51) International Patent Classification (IPC): 
A61L 24/00(2006.01)
A61L 24/10(2006.01)
(86) International application number:
PCT/US2009/038666
(87) International publication number:
WO 2009/154840 (23.12.2009 Gazette 2009/52)

(54)

COMPOSITIONS AND METHODS USING STEM CELLS IN CUTANEOUS WOUND HEALING

ZUSAMMENSETZUNGEN UND VERFAHREN UNTER VERWENDUNG VON STAMMZELLEN ZUR WUNDHEILUNG AUF DER HAUT

COMPOSITIONS ET MÉTHODES UTILISANT DES CELLULES SOUCHES DANS LA CICATRISATION DE PLAIES CUTANÉES


(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
Designated Extension States:
AL BA RS

(30) Priority: 27.03.2008 US 39941 P

(43) Date of publication of application:
16.02.2011 Bulletin 2011/07

(73) Proprietor: Caladrius Biosciences, Inc.
New York, NY 10170 (US)

(72) Inventor:
  • FALANGA, Vincent
    Boston, MA 02115 (US)

(74) Representative: Pohlman, Sandra M. et al
df-mp Dörries Frank-Molnia & Pohlman Patentanwälte Rechtsanwälte PartG mbB Theatinerstrasse 16
80333 München
80333 München (DE)


(56) References cited: : 
EP-A1- 1 900 370
US-A1- 2006 095 075
US-A1- 2004 191 225
US-A1- 2007 286 881
   
  • R.W.E PIKAART: "Human Fibrin as a Cell Carrier for Heart Valve Tissue Engineering", January 2008 (2008-01), Thesis from Eindhoven Universoty of Technology, Eindhoven University of Technology, XP002700008, pages 1-x, * page 6, paragraph 2.1.1 - page 7, paragraph 2.1.3 * * page 11, paragraph 3.1.1 - page 14, paragraph 3.2.3 *
  • O'LEARY R ET AL.: 'A novel in vitro dermal wound-healing model incorporating a response to mechanical wounding and repopulation of a fibrin provisional matrix.' IN VITRO CELL DEV BIOL ANIM. vol. 39, no. 5-6, May 2003, pages 204 - 207, XP008051297
  • KUCIA M ET AL.: 'Physiological and pathological consequences of identification of very small embryonic like (VSEL) stem cells in adult bone marrow.' J. PHYSIOL. PHARMACOL. vol. 57, no. SUP.5, November 2006, pages 5 - 18, XP002604058
  • GORODETSKY R ET AL.: 'Haptotactic and growth stimulatory effects of fibrin(ogen) and thrombin on cultured fibroblasts.' J LAB CLIN MED. vol. 131, no. 3, March 1998, pages 269 - 280, XP009046579
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).