(19)

(11)

EP 2 283 132 A2

(12)

(88) Date of publication A3: 23.12.2009 (43) Date of publication: 16.02.2011 Bulletin 2011/07 (21) Application number: 09740014.7 (22) Date of filing: 04.05.2009

(51) International Patent Classification (IPC):  C12N 15/10(2006.01) C07H 21/02(2006.01) C12N 15/11(2006.01) C12Q 1/68(2006.01) (86) International application number: PCT/US2009/042723 (87) International publication number: WO 2009/135212 (05.11.2009 Gazette 2009/45)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA RS (30) Priority: 02.05.2008 US 50046 (71) Applicant: Epicentre Technologies Corporation Madison, WI 53713 (US)	(72) Inventors: JENDRISAK, Jerome, J. Madison WI 53705 (US) VAIDYANATHAN, Ramesh Madison WI 53717 (US) DAHL, Gary Madison WI 53726 (US) (74) Representative: Dehmel, Albrecht  Dehmel & Bettenhausen Patentanwälte Herzogspitalstrasse 11 80331 München 80331 München (DE)