(19)

(11)

EP 2 285 420 A2

(12)

(88) Date of publication A3: 18.03.2010 (43) Date of publication: 23.02.2011 Bulletin 2011/08 (21) Application number: 09738115.6 (22) Date of filing: 27.04.2009

(51) International Patent Classification (IPC):  A61K 49/00(2006.01) G01N 33/48(2006.01) G01N 33/52(2006.01) A61P 35/00(2006.01) A61K 31/722(2006.01) G01N 33/00(2006.01) G01N 33/50(2006.01) G01N 33/574(2006.01) A61K 31/785(2006.01) A61K 38/02(2006.01) (86) International application number: PCT/EP2009/055069 (87) International publication number: WO 2009/133071 (05.11.2009 Gazette 2009/45)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA RS (30) Priority: 30.04.2008 EP 08425304 (71) Applicant: Consorzio Per Il Centro Di Biomedicina Molecolare SCRL 34012 Trieste (TS) (IT)	(72) Inventor: KROL, Silke I-34012 Basovizza (Trieste) (IT) (74) Representative: Spadaro, Marco et al Studio Associato LEONE & SPADARO Viale Europa, 15 00144 Roma 00144 Roma (IT)