(19)

(11)

EP 2 285 778 A1

(12)

(43) Date of publication: 23.02.2011 Bulletin 2011/08 (21) Application number: 09733745.5 (22) Date of filing: 22.04.2009

(51) International Patent Classification (IPC):  C07D 213/81(2006.01) A61K 51/04(2006.01) A61P 43/00(2006.01) C07D 215/48(2006.01) C07D 215/54(2006.01) A61K 101/02(2006.01) A61B 8/13(2006.01) A61P 35/00(2006.01) C07D 213/82(2006.01) C07D 215/50(2006.01) C07D 401/06(2006.01) (86) International application number: PCT/AU2009/000504 (87) International publication number: WO 2009/129573 (29.10.2009 Gazette 2009/44)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA RS (30) Priority: 22.04.2008 AU 2008901989 (71) Applicant: CRC for Biomedical Imaging Development Ltd Bundoora, VIC 3083 (AU)	(72) Inventors: KATSIFIS, Andrew Lucas Heights Sydney, NSW 2234 (AU) GREGURIC, Ivan Lucas Heights, NSW 2234 (AU) (74) Representative: Swinkels, Bart Willem  Nederlandsch Octrooibureau J. W. Frisolaan 13 2517 JS Den Haag 2517 JS Den Haag (NL)