(19)
(11) EP 2 296 621 A1

(12)

(43) Date of publication:
23.03.2011 Bulletin 2011/12

(21) Application number: 09751516.7

(22) Date of filing: 20.05.2009
(51) International Patent Classification (IPC): 
A61K 9/00(2006.01)
A61K 31/58(2006.01)
A61K 31/519(2006.01)
A61K 9/16(2006.01)
A61K 31/57(2006.01)
(86) International application number:
PCT/US2009/044732
(87) International publication number:
WO 2009/143288 (26.11.2009 Gazette 2009/48)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
Designated Extension States:
AL BA RS

(30) Priority: 20.05.2008 US 54511 P
20.05.2008 US 54519 P
20.05.2008 US 54506 P

(71) Applicants:
  • Yale University
    New Haven, CT 06511 (US)
  • University of Iowa Research Foundation
    Iowa City, IA 52242-5500 (US)

(72) Inventors:
  • LAVIK, Erin
    Cleveland Heights, OH 44118 (US)
  • BERTRAM, James
    New Haven CT 06511 (US)
  • SALUJA, Sandeep
    Fair Lawn NJ 07410 (US)
  • KEUHN, Markus
    Amana IA 52203 (US)
  • KWON, Young, H.
    Iowa City IA 52246 (US)
  • ROBINSON, Rebecca
    East Point GA 30344 (US)
  • HUANG, John, J.
    Hamden CT 06518 (US)

(74) Representative: Bassett, Richard Simon 
Potter Clarkson LLP Park View House 58 The Ropewalk
Nottingham NG1 5DD
Nottingham NG1 5DD (GB)

   


(54) BIODEGRADABLE SUSTAINED-RELEASE POLYMERIC MICROPARTICULATES COMPRISING A HYDROPHOBIC DRUG AND DETERMINED FOR OPHTHALMIC USE