(19)
(11) EP 2 303 883 A1

(12)

(43) Date of publication:
06.04.2011 Bulletin 2011/14

(21) Application number: 08759614.4

(22) Date of filing: 15.05.2008
(51) International Patent Classification (IPC): 
C07D 473/30(2006.01)
A61P 9/12(2006.01)
 A61K 31/522(2006.01)
(86) International application number:
PCT/EP2008/055941
(87) International publication number:
WO 2009/138122 (19.11.2009 Gazette 2009/47)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
Designated Extension States:
AL BA MK RS

(71) Applicant: Novartis AG
4056 Basel (CH)

(72) Inventors:
  • TSCHINKE, Vincenzo
    CH-4102 Binningen (CH)
  • NAPOLETANO, Mauro
    I-20127 Milano (IT)
  • HAACK, Thomas
    I-22100 Como (IT)

(74) Representative: von Sprecher, Georg et al
Novartis Pharma AG Patent Department
4002 Basel
4002 Basel (CH)

   


(54) PURINE DERIVATIVES FURTHER COMPRISING A MERCAPTO-ACYLAMINO GROUP AS NEUTRAL ENDOPEPTIDASE INHIBITORS