(19)
(11) EP 2 315 833 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
27.05.2015 Bulletin 2015/22

(45) Mention of the grant of the patent:
01.04.2015 Bulletin 2015/14

(21) Application number: 09800733.9

(22) Date of filing: 20.05.2009
(51) International Patent Classification (IPC): 
C12N 15/12(2006.01)
C12N 15/33(2006.01)
C07K 14/705(2006.01)
A61K 48/00(2006.01)
C12N 15/63(2006.01)
C07K 14/47(2006.01)
(86) International application number:
PCT/US2009/044753
(87) International publication number:
WO 2010/011404 (28.01.2010 Gazette 2010/04)

(54)

VECTORS FOR DELIVERY OF LIGHT-SENSITIVE PROTEINS AND METHODS OF USE

VEKTOREN ZUR FREISETZUNG LICHTEMPFINDLICHER PROTEINE UND ANWENDUNGSVERFAHREN DAFÜR

VECTEURS POUR LA DÉLIVRANCE DE PROTÉINES PHOTOSENSIBLES ET PROCÉDÉS D'UTILISATION


(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

(30) Priority: 20.05.2008 US 54571 P
14.11.2008 US 199241 P
26.11.2008 US 200430 P

(43) Date of publication of application:
04.05.2011 Bulletin 2011/18

(60) Divisional application:
15160919.5

(73) Proprietors:
  • Eos Neuroscience, Inc.
    San Francisco, CA 94109-1880 (US)
  • University of Florida Research Foundation, Inc.
    Gainesville, FL 32611-5500 (US)

(72) Inventors:
  • HORSAGER, Alan
    Los Angeles CA 90049 (US)
  • HAUSWIRTH, William
    Gainesville FL 32608 (US)
  • LIU, Jianwen
    Gainesville FL 32605 (US)

(74) Representative: Walker, Ross Thomson 
Forresters Skygarden Erika-Mann-Strasse 11
80636 München
80636 München (DE)


(56) References cited: : 
WO-A2-2007/131180
US-A1- 2009 088 399
   
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  • LAGALI P S ET AL: "Light-activated channels targeted to ON bipolar cells restore visual function inretinal degeneration", NATURE NEUROSCIENCE, NATURE AMERICA, INC, US, vol. 11, no. 6, 1 June 2008 (2008-06-01), pages 667-675, XP003031411, ISSN: 1097-6256
  • ZHONG LI ET AL: "Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, US, vol. 105, no. 22, 3 June 2008 (2008-06-03) , pages 7827-7832, XP002493284, ISSN: 0027-8424, DOI: 10.1073/PNAS.0802866105
  • NGUYEN J B ET AL: "Convection-enhanced delivery of AAV-2 combined with heparin increases TK gene transfer in the rat brain", NEUROREPORT,, vol. 12, no. 9, 3 July 2001 (2001-07-03), pages 1961-1964, XP002974882, ISSN: 0959-4965, DOI: 10.1097/00001756-200107030-00037
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  • HARVEY A R ET AL: "Intravitreal injection of adeno-associated viral vectors results in the transduction of different types of retinal neurons in neonatal and adult rats: A comparison with lentiviral vectors", MOLECULAR AND CELLULAR NEUROSCIENCE, vol. 21, no. 1, September 2002 (2002-09), pages 141-157, ISSN: 1044-7431
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