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(11) |
EP 2 322 646 A8 |
| (12) |
CORRECTED EUROPEAN PATENT APPLICATION |
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Note: Bibliography reflects the latest situation |
| (15) |
Correction information: |
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Corrected version no 1 (W1 A1) |
| (48) |
Corrigendum issued on: |
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16.05.2012 Bulletin 2012/20 |
| (43) |
Date of publication: |
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18.05.2011 Bulletin 2011/20 |
| (22) |
Date of filing: 08.11.2005 |
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| (51) |
International Patent Classification (IPC):
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| (84) |
Designated Contracting States: |
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DE ES FR GB |
| (30) |
Priority: |
08.11.2004 JP 2004323770
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| (62) |
Application number of the earlier application in accordance with Art. 76 EPC: |
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05803016.4 / 1816211 |
| (71) |
Applicant: Mitsubishi Chemical Medience Corporation |
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Tokyo 108-8559 (JP) |
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| (72) |
Inventor: |
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- Ono, Tomoko
Tokyo 108-8559 (JP)
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| (74) |
Representative: Vossius & Partner |
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Siebertstrasse 4
81675 München
81675 München (DE) |
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Remarks: |
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This application was filed on 19-01-2011 as a divisional application to the application
mentioned under INID code 62. |
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| (54) |
Method of detecting platelet thrombosis or organ failure |
(57) A method of detecting platelet thrombosis or organ failure in a patient suffering
from disseminated intravascular coagulation (DIC) or systemic inflammatory response
syndrome (SIRS), comprising analyzing a von Willebrand factor-cleaving protease and/or
a cleaving factor thereof, is disclosed. A kit for detecting platelet thrombosis or
organ failure in a patient suffering from DIC or SIRS, comprising an antibody or a
fragment thereof which specifically binds to a von Willebrand factor-cleaving protease,
and/or an antibody or a fragment thereof which specifically binds to a cleaving factor
of the von Willebrand factor-cleaving protease, is disclosed.