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(11)

EP 2 328 405 A1

(12)

(43) Date of publication: 08.06.2011 Bulletin 2011/23 (21) Application number: 09810727.9 (22) Date of filing: 31.08.2009

(51) International Patent Classification (IPC):  A01H 5/00(2006.01) C12N 5/10(2006.01) C12N 15/82(2006.01) (86) International application number: PCT/US2009/055555 (87) International publication number: WO 2010/025465 (04.03.2010 Gazette 2010/09)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR Designated Extension States: AL BA RS (30) Priority: 29.08.2008 US 190581 P (71) Applicants: Los Alamos National Security, LLC Los Alamos, NM 87545 (US) University of Maine System Board of Trustees Bangor, ME 04401 (US)	(72) Inventors: UNKEFER, Pat J. Los Alamos, New Mexico 87544 (US) ANDERSON, Penelope S. Los Alamos, New Mexico 87544 (US) KNIGHT, Thomas J. Raymond, Maine 04701 (US) (74) Representative: Marshall, Cameron John et al Carpmaels & Ransford One Southampton Row London WC1B 5HA London WC1B 5HA (GB)