(19)
(11) EP 2 329 017 A2

(12)

(88) Date of publication A3:
25.03.2010

(43) Date of publication:
08.06.2011 Bulletin 2011/23

(21) Application number: 09785836.9

(22) Date of filing: 09.02.2009
(51) International Patent Classification (IPC): 
C12N 15/09(2006.01)
C12N 9/22(2006.01)
 C12N 15/90(2006.01)
(86) International application number:
PCT/IB2009/000486
(87) International publication number:
WO 2010/015899 (11.02.2010 Gazette 2010/06)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
Designated Extension States:
AL BA RS

(30) Priority: 04.08.2008 WO PCT/IB2008/002999
12.12.2008 WO PCT/IB2008/003744

(71) Applicant: Cellectis
93235 Romainville Cedex (FR)

(72) Inventors:
  • PAQUES, Frédéric
    F-92340 Bourg-la-Reine (FR)
  • GRIZOT, Sylvestre
    F-92250 La Garenne Colombes (FR)
  • DUCHATEAU, Philippe
    F-93190 Livry Gargan (FR)

(74) Representative: Thomas, Dean et al
Cabinet Ores 36 rue de St Pétersbourg
75008 Paris
75008 Paris (FR)

   


(54) NOVEL METHOD TO GENERATE MEGANUCLEASES WITH ALTERED CHARACTERISTICS