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(11)

EP 2 331 507 A2

(12)

(88) Date of publication A3: 10.06.2010 (43) Date of publication: 15.06.2011 Bulletin 2011/24 (21) Application number: 09748156.8 (22) Date of filing: 17.09.2009

(51) International Patent Classification (IPC):  C07D 213/82(2006.01) (86) International application number: PCT/JP2009/066840 (87) International publication number: WO 2010/032875 (25.03.2010 Gazette 2010/12)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR Designated Extension States: AL BA RS (30) Priority: 18.09.2008 US 97979 P (71) Applicant: Astellas Pharma Inc. Tokyo 103-8411 (JP)

(72) Inventors: TERASAWA, Takeshi Tokyo 103-8411 (JP) SHIGENAGA, Shinji Tokyo 103-8411 (JP) ITOH, Shinji Tokyo 103-8411 (JP) MAEDA, Jun Tokyo 103-8411 (JP) WATANABE, Hideyuki Tokyo 103-8411 (JP) KUBO, Satoshi Tokyo 103-8411 (JP) ISHII, Noe Tsukuba-shi Ibaragi 305-0817 (JP) (74) Representative: Gille Hrabal Struck Neidlein Prop Roos  Patentanwälte Brucknerstrasse 20 40593 Düsseldorf 40593 Düsseldorf (DE)