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(11)

EP 2 331 691 A1

(12)

(43) Date of publication: 15.06.2011 Bulletin 2011/24 (21) Application number: 09811872.2 (22) Date of filing: 11.03.2009

(51) International Patent Classification (IPC):  C12N 15/31(2006.01) C12N 1/21(2006.01) C12N 15/63(2006.01) C12R 1/145(2006.01) (86) International application number: PCT/US2009/036868 (87) International publication number: WO 2010/027531 (11.03.2010 Gazette 2010/10)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA RS (30) Priority: 07.09.2008 WO PCT/US2008/075515 05.09.2008 US 205845 (71) Applicant: Cobalt Technologies, Inc. Mountain View, CA 94043 (US)	(72) Inventors: BURNS-GUYDLSH, Stacy, M. Campbell CA 95008 (US) CONTAG, Pamela, Reilly San Jose CA 95129 (US) (74) Representative: Hart, Deborah Mary  Kilburn & Strode LLP 20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)