(19) |
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(11) |
EP 2 338 902 A8 |
(12) |
CORRECTED EUROPEAN PATENT APPLICATION |
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Note: Bibliography reflects the latest situation |
(15) |
Correction information: |
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Corrected version no 1 (W1 A1) |
(48) |
Corrigendum issued on: |
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03.08.2011 Bulletin 2011/31 |
(43) |
Date of publication: |
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29.06.2011 Bulletin 2011/26 |
(22) |
Date of filing: 29.04.2008 |
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(51) |
International Patent Classification (IPC):
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(84) |
Designated Contracting States: |
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AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL
PT RO SE SI SK TR |
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Designated Extension States: |
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AL BA MK RS |
(30) |
Priority: |
02.05.2007 EP 07107344
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(62) |
Application number of the earlier application in accordance with Art. 76 EPC: |
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08736618.3 / 2152731 |
(71) |
Applicant: Intercell AG |
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1030 Vienna (AT) |
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(72) |
Inventors: |
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- Bakshi, Sharmila
Kenton, Harrow
HA3 0LR Middlesex (GB)
- Cipps, Thomas
1140 Vienna (AT)
- Hanner, Markus
3013 Pressbaum (AT)
- Pikalo, Jutta
9162 Strau (AT)
- Satke, Christina
1060 Vienna (AT)
- Nagy, Eszter
1070 Vienna (AT)
- Lundberg, Urban
3013 Pressbaum (AT)
- Wakefield, Dagmar
NSW 2483 Ocean Shores (AU)
- Meinke, Andreas
3013 Pressbaum (AT)
- Noiges, Birgit
1050 Vienna (AT)
- Stierschneider, Ulrike
1070 Vienna (AT)
- von Gabain, Alexander
1180 Vienna (AT)
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(74) |
Representative: Bösl, Raphael Konrad |
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Isenbruck Bösl Hörschler LLP
Patentanwälte
Prinzregentenstrasse 68 81675 München 81675 München (DE) |
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Remarks: |
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The complete document including Reference Tables and the Sequence Listing can be downloaded
from the EPO website |
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Remarks: |
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This application was filed on 27-09-2010 as a divisional application to the application
mentioned under INID code 62. |
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(57) The present invention relates to isolated nucleic acid molecules which encode an
antigen, a vector which comprises such nucleic acid molecule, and a host cell comprising
such vector. Furthermore, the invention provides antigens from a
Klebsiella species, as well as fragments and variants thereof, a process for producing such
antigens, and a process for producing a cell, which expresses such antigen. Moreover,
the present invention provides antibodies binding to such antigen, a hybridoma cell
producing such antibodies, methods for producing such antibodies, a pharmaceutical
composition comprising such nucleic acid molecule, antigen, vector or antibody, the
use of such nucleic acid molecule, antigen, vector or antibody for the preparation
of a pharmaceutical composition, methods for identifying an antagonist capable of
binding such antigen or of reducing or inhibiting the interaction activity of such
antigen, methods for diagnosing an infection and methods for the treatment or prevention
of an infection. More specifically such antigens are produced by or associated with
bacterial pathogens causing nosocomial infections or bacterial infections caused by
Klebsiella pneumoniae.