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EP 2 344 487 A1

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(43) Date of publication: 20.07.2011 Bulletin 2011/29 (21) Application number: 09815517.9 (22) Date of filing: 14.09.2009

(51) International Patent Classification (IPC):  C07D 417/14(2006.01) A61K 31/506(2006.01) A61K 31/4709(2006.01) A61P 31/14(2006.01) (86) International application number: PCT/CA2009/001237 (87) International publication number: WO 2010/034105 (01.04.2010 Gazette 2010/13)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR Designated Extension States: AL BA RS (30) Priority: 23.09.2008 US 99292 P 12.06.2009 US 186632 P (71) Applicant: Boehringer Ingelheim International GmbH 55216 Ingelheim (DE)

(72) Inventors: O'MEARA, Jeffrey Laval Québec H7S 2G5 (CA) BORDELEAU, Josée Laval Québec H7S 2G5 (CA) GORYS, Vida Laval Québec H7S 2G5 (CA) LEBLANC, Mélissa Laval Québec H7S 2G5 (CA) LENHARDT, Kirsten 55216 Ingelheim am Rhein (DE) LLINAS-BRUNET, Montse Laval Québec H7S 2G5 (CA) PARISIEN, Mathieu Laval Québec H7S 2G5 (CA) POUPART, Marc-André Laval Québec H7S 2G5 (CA) (74) Representative: Hammann, Heinz  Boehringer Ingelheim GmbH Corporate Patents Binger Strasse 173 55216 Ingelheim am Rhein 55216 Ingelheim am Rhein (DE)