| (84) |
Designated Contracting States: |
|
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO
PL PT RO SE SI SK SM TR |
| (30) |
Priority: |
31.10.2008 JP 2008281065
|
| (43) |
Date of publication of application: |
|
20.07.2011 Bulletin 2011/29 |
| (73) |
Proprietor: Intellectual Property Strategy Network, Inc. |
|
Chiyoda-ku
Tokyo 100-0005 (JP) |
|
| (72) |
Inventors: |
|
- AKIYOSHI Kazunari
Tokyo 113-8510 (JP)
- KIYONO Hiroshi
Tokyo 112-0013 (JP)
- YUKI Yoshikazu
Tokyo 113-0033 (JP)
- NOCHI Tomonori
Chapel Hill
North Carolina 27516 (US)
|
| (74) |
Representative: Tollervey, Rebecca Marie et al |
|
Mewburn Ellis LLP City Tower
40 Basinghall Street
London EC2V 5DE City Tower
40 Basinghall Street
London EC2V 5DE (GB) |
| (56) |
References cited: :
WO-A1-98/09650 JP-A- 2008 231 343
|
JP-A- 2007 252 304 US-B1- 6 656 481
|
|
| |
|
|
- KAZUHIDE TSUJI ET AL: "Induction of immune response against NY-ESO-1 by CHP-NY-ESO-1
vaccination and immune regulation in a melanoma patient", CANCER IMMUNOLOGY, IMMUNOTHERAPY,
SPRINGER, BERLIN, DE, vol. 57, no. 10, 1 March 2008 (2008-03-01) , pages 1429-1437,
XP019624401, ISSN: 1432-0851
- AKIYOSHI K ET AL: "Self-assembled hydrogel nanoparticle of cholesterol-bearing pullulan
as a carrier of protein drugs: Complexation and stabilization of insulin", JOURNAL
OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM, NL, vol. 54, no. 3, 14 August 1998 (1998-08-14),
pages 313-320, XP004147061, ISSN: 0168-3659, DOI: 10.1016/S0168-3659(98)00017-0
- S. KITANO ET AL: "HER2-Specific T-Cell Immune Responses in Patients Vaccinated with
Truncated HER2 Protein Complexed with Nanogels of Cholesteryl Pullulan", CLINICAL
CANCER RESEARCH, vol. 12, no. 24, 15 December 2006 (2006-12-15), pages 7397-7405,
XP055062075, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-06-1546
- SHINICHI KAGEYAMA ET AL: "Humoral immune responses in patients vaccinated with 1-146
HER2 protein complexed with cholesteryl pullulan nanogel", CANCER SCIENCE, vol. 99,
no. 3, 1 March 2008 (2008-03-01), pages 601-607, XP055062074, ISSN: 1347-9032, DOI:
10.1111/j.1349-7006.2007.00705.x
- BACON A ET AL: "Carbohydrate biopolymers enhance antibody responses to mucosally delivered
vaccine antigens", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MACROBIOLOGY, USA,
vol. 68, no. 10, 1 January 2001 (2001-01-01), pages 5764-5770, XP009169468, ISSN:
0019-9567
- ILLUM L ET AL: "CHITOSAN AS A NOVEL NASAL DELIVERY SYSTEM FOR VACCINES", ADVANCED
DRUG DELIVERY REVIEWS, ELSEVIER BV, AMSTERDAM, NL, vol. 51, no. 1-03, 23 September
2001 (2001-09-23), pages 81-96, XP001115064, ISSN: 0169-409X, DOI: 10.1016/S0169-409X(01)00171-5
- DES RIEUX A ET AL: "Nanoparticles as potential oral delivery systems of proteins and
vaccines: A mechanistic approach", JOURNAL OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM,
NL, vol. 116, no. 1, 10 November 2006 (2006-11-10), pages 1-27, XP024957681, ISSN:
0168-3659, DOI: 10.1016/J.JCONREL.2006.08.013 [retrieved on 2006-11-10]
- PEEK L J ET AL: "Nanotechnology in vaccine delivery", ADVANCED DRUG DELIVERY REVIEWS,
ELSEVIER BV, AMSTERDAM, NL, vol. 60, no. 8, 22 May 2008 (2008-05-22), pages 915-928,
XP022624679, ISSN: 0169-409X, DOI: 10.1016/J.ADDR.2007.05.017 [retrieved on 2008-02-07]
- NOCHI TOMONORI ET AL: "Nanogel antigenic protein-delivery system for adjuvant-free
intranasal vaccines", NATURE MATERIALS, NATURE PUBLISHING GROUP, GB, vol. 9, no. 7,
1 July 2010 (2010-07-01), pages 572-578, XP009169464, ISSN: 1476-1122, DOI: 10.1038/NMAT2784
- TOITA SAYAKA ET AL: "Protein-conjugated quantum dots effectively delivered into living
cells by a cationic nanogel.", JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY MAY 2008,
vol. 8, no. 5, May 2008 (2008-05), pages 2279-2285, XP009178643, ISSN: 1533-4880
- SATOH K ET AL: "Nanoparticle of cholesterol-bearing pullulan as a carrier of anticancer
drugs", EUROPEAN JOURNAL OF CANCER. SUPPLEMENT, PERGAMON, OXFORD, GB, vol. 6, no.
9, 1 July 2008 (2008-07-01), page 139, XP022834053, ISSN: 1359-6349, DOI: 10.1016/S1359-6349(08)71707-5
[retrieved on 2008-07-01]
- R.J Soane ET AL: "Evaluation of the clearance characteristics of bioadhesive systems
in humans", International Journal of Pharmaceutics, vol. 178, no. 1, 1 February 1999
(1999-02-01), pages 55-65, XP055124843, ISSN: 0378-5173, DOI: 10.1016/S0378-5173(98)00367-6
|
|