(19)
(11) EP 2 351 764 A8

(12) CORRECTED EUROPEAN PATENT APPLICATION
published in accordance with Art. 153(4) EPC

(15) Correction information:
Corrected version no 1 (W1 A1)

(48) Corrigendum issued on:
21.09.2011 Bulletin 2011/38

(43) Date of publication:
03.08.2011 Bulletin 2011/31

(21) Application number: 09823291.1

(22) Date of filing: 27.10.2009
(51) International Patent Classification (IPC): 
C07H 13/06(2006.01)
A61P 31/00(2006.01)
A61P 35/00(2006.01)
A61P 39/02(2006.01)
 A61K 31/7024(2006.01)
A61P 31/04(2006.01)
A61P 37/04(2006.01)
(86) International application number:
PCT/JP2009/005650
(87) International publication number:
WO 2010/050178 (06.05.2010 Gazette 2010/18)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

(30) Priority: 31.10.2008 JP 2008282613
27.02.2009 JP 2009046824

(71) Applicant: Otsuka Chemical Co., Ltd.
Osaka-shi, Osaka 540-0021 (JP)

(72) Inventors:
  • NISHIZAWA, Mugio
    Tokushima-shi Tokushima 770-0872 (JP)
  • IMAGAWA, Hiroshi
    Tokushima-shi Tokushima 770-0866 (JP)
  • YAMAMOTO, Hirofumi
    Tokushima-shi Tokushima 770-0944 (JP)
  • SAKURAI, Jun
    Tokushima-shi Tokushima 771-4263 (JP)
  • ODA, Masataka
    Tokushima-shi Tokushima 770-0944 (JP)

(74) Representative: Niizuma, Yo et al
Niizuma Wasner GmbH Lörracherstrasse 122
CH-4125 Riehen
CH-4125 Riehen (CH)

   


(54) TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND


(57) It is an object of the present invention to provide a trehalose compound having high immunopotentiating activity and low toxicity. The trehalose compound is represented by formula (1). (In the formula, X and X' each represents a phenyl, a naphtyl, R1-CHR1- (wherein R1 and R2 each represents a C7-C21 alkyl group or the like) or the like; and n and n' each independently represents an integer of 0-3). The compound exhibits a high activating effect on macrophages and neutrophils.