(19)
(11) EP 2 361 303 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
10.08.2016 Bulletin 2016/32

(45) Mention of the grant of the patent:
06.04.2016 Bulletin 2016/14

(21) Application number: 09744160.4

(22) Date of filing: 02.11.2009
(51) International Patent Classification (IPC): 
C12N 5/0775(2010.01)
A61P 13/12(2006.01)
 C12N 5/074(2010.01)
A61K 35/22(2006.01)
(86) International application number:
PCT/EP2009/064468
(87) International publication number:
WO 2010/052192 (14.05.2010 Gazette 2010/19)

(54)

AN ISOLATED MULTIPOTENT MESENCHYMAL STEM CELL FROM HUMAN ADULT GLOMERULI (HGL-MSC), A METHOD OF PREPARING THEREOF AND USES THEREOF IN THE REGENERATIVE MEDICINE OF THE KIDNEY

ISOLIERTE MULTIPOTENTE MESENCHYMSTAMMZELLE AUS HUMANEN ADULTEN GLOMERULI (HGL-MSC), VERFAHREN ZU DEREN HERSTELLUNG UND DEREN ANWENDUNGEN IN DER MEDIZIN ZUR NIERENREGENERATION

CELLULE SOUCHE DE TYPE STROMALE MULTIPOTENTE ISOLÉE DE GLOMÉRULES HUMAINS ADULTES (HGL-MSC), SON PROCÉDÉ DE PRÉPARATION ET SES UTILISATIONS EN MÉDECINE RÉGÉNÉRATIVE DU REIN

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

(30) Priority: 04.11.2008 EP 08425708

(43) Date of publication of application:
31.08.2011 Bulletin 2011/35

(73) Proprietor: Fresenius Medical Care Deutschland GmbH
61352 Bad Homburg (DE)

(72) Inventors:
  • CAMUSSI, Giovanni
    I-10133 Torino (IT)
  • BRUNO, Stefania
    I-10064 Pinerolo (TO) (IT)
  • BUSSOLATI, Benedetta
    I-10024 Moncalieri (TO) (IT)

(74) Representative: Comoglio, Elena et al
Jacobacci & Partners S.p.A. Corso Emilia 8
10152 Torino
10152 Torino (IT)


(56) References cited: : 
WO-A-2007/125088
 WO-A-2008/045498
   
  • SCHWAB K E ET AL: "Co-expression of two perivascular cell markers isolates mesenchymal stem-like cells from human endometrium" HUMAN REPRODUCTION (OXFORD), vol. 22, no. 11, November 2007 (2007-11), pages 2903-2911, XP002512778 ISSN: 0268-1161
  • LONDOLFO DA SILVA MEIRELLES ET AL: "Mesenchymal stem cells reside in virtually all post-natal organs and tissues" JOURNAL OF CELL SCIENCE, CAMBRIDGE UNIVERSITY PRESS, LONDON, GB, vol. 119, no. 11, 1 June 2006 (2006-06-01), pages 2204-2213, XP002488374 ISSN: 0021-9533
  • SAGRINATI C ET AL: "Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys" JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, WILLIAMS AND WILKINS, BALTIMORE, MD, US, vol. 17, no. 9, 1 September 2006 (2006-09-01), pages 2443-2456, XP002454240 ISSN: 1046-6673
  • BRUNO STEFANIA ET AL: "Isolation and characterization of resident mesenchymal stem cells in human glomeruli." STEM CELLS AND DEVELOPMENT 2009 JUL-AUG, vol. 18, no. 6, July 2009 (2009-07), pages 867-880, XP002567261 ISSN: 1557-8534
  • PERRY JULIE ET AL: "Type IV collagen induces podocytic features in bone marrow stromal stem cells in vitro", JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, vol. 17, no. 1, January 2006 (2006-01), pages 66-76, ISSN: 1046-6673
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).