(19)
(11) EP 2 364 367 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
23.08.2017 Bulletin 2017/34

(45) Mention of the grant of the patent:
26.04.2017 Bulletin 2017/17

(21) Application number: 09760657.8

(22) Date of filing: 10.11.2009
(51) International Patent Classification (IPC): 
C12Q 1/68(2006.01)
(86) International application number:
PCT/US2009/063900
(87) International publication number:
WO 2010/054386 (14.05.2010 Gazette 2010/19)

(54)

METHOD UTILIZING MICRORNA FOR DETECTING INTERSTITIAL LUNG DISEASE

VERFAHREN MIT MIKRORNA ZUR ERKENNUNG VON INTERSTITIELLER LUNGENERKRANKUNG

PROCÉDÉ UTILISE DU MICROARN POUR LA DÉTECTION DE LA PNEUMONIE INTERSTITIEL


(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

(30) Priority: 10.11.2008 US 112985 P

(43) Date of publication of application:
14.09.2011 Bulletin 2011/37

(60) Divisional application:
17164882.7

(73) Proprietors:
  • Battelle Memorial Institute
    Columbus, OH 43201-2693 (US)
  • Institute for Systems Biology
    Seattle WA 98103-8904 (US)
  • The Ohio State University Research Foundation
    Columbus, OH 43210-1063 (US)

(72) Inventors:
  • GALAS, David
    Seattle WA 98119 (US)
  • GELINAS, Richard, Evan
    Seattle WA 98144 (US)
  • MARSH, Clay, Braden
    Columbus OH 43221 (US)
  • PIPER, Melissa, Garnet
    Dublin OH 43017 (US)
  • WANG, Kai
    Bellevue WA 98006 (US)
  • ZHANG, Shile
    Seattle WA 98103 (US)

(74) Representative: Kador & Partner 
Corneliusstraße 15
80469 München
80469 München (DE)


(56) References cited: : 
WO-A2-00/60117
WO-A2-2008/073915
WO-A2-2007/103808
US-A1- 2006 019 286
   
  • TAKAMIZAWA J ET AL: "Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival" CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD., US, vol. 64, 1 June 2004 (2004-06-01), pages 3753-3756, XP002385720 ISSN: 0008-5472
  • CHEN X ET AL: "Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases" CELL RESEARCH - XIBAO YANJIU, NATURE PUBLISHING GROUP, GB, CN, vol. 18, no. 10, 1 October 2008 (2008-10-01), pages 997-1006, XP002552942 ISSN: 1001-0602 [retrieved on 2008-09-02]
  • NANA-SINKAM S.P. ET AL.,: "integrating the micrornome into the study of lung disease" AM. J. RESPIR. CRIT. CARE MED, vol. 179, 11 September 2008 (2008-09-11), pages 4-10, XP002571588
  • SUNG-LIANG YU ET AL: 'MicroRNA signature predicts survival and relapse in lung cancer', [Online] vol. 13, no. 1, 08 January 2008, pages 48 - 57, XP002681411 DOI: 10.1016/J.CCR.2007.12.008 ISSN: 1535-6108 CANCER CELL, CELL PRESS, US Retrieved from the Internet: <URL:http://www.sciencedirect.com/science/a rticle/pii/S1535610807003753>
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).