(19)
(11) EP 2 368 899 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
18.10.2017 Bulletin 2017/42

(45) Mention of the grant of the patent:
06.09.2017 Bulletin 2017/36

(21) Application number: 09829169.3

(22) Date of filing: 27.11.2009
(51) International Patent Classification (IPC): 
C07K 7/06(2006.01)
A61K 39/00(2006.01)
A61P 31/16(2006.01)
A61K 9/00(2006.01)
A61K 39/145(2006.01)
A61K 9/127(2006.01)
A61K 47/28(2006.01)
A61P 37/04(2006.01)
C07K 14/005(2006.01)
A61K 39/12(2006.01)
(86) International application number:
PCT/JP2009/070053
(87) International publication number:
WO 2010/061924 (03.06.2010 Gazette 2010/22)

(54)

AVIAN INFLUENZA VACCINE

IMPFSTOFF GEGEN VOGELGRIPPE

VACCIN CONTRE LA GRIPPE AVIAIRE


(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

(30) Priority: 28.11.2008 JP 2008303444

(43) Date of publication of application:
28.09.2011 Bulletin 2011/39

(73) Proprietors:
  • JAPAN AS REPRESENTED BY THE DIRECTOR-GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES
    Shinjuku-ku Tokyo 162-8640 (JP)
  • NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
    Kita-ku Sapporo-shi Hokkaido 060-0808 (JP)
  • Saitama Medical University
    Iruma-gun, Saitama 350-0495 (JP)
  • NOF CORPORATION
    Tokyo 150-6019 (JP)

(72) Inventors:
  • UCHIDA, Tetsuya
    Tokyo 162-8640 (JP)
  • TANEICHI, Maiko
    Tokyo 162-8640 (JP)
  • KAJINO, Kiichi
    Sapporo-shi Hokkaido 060-0808 (JP)
  • MATSUI, Masanori
    Iruma-gun Saitama 350-0495 (JP)
  • ODA, Hiroshi
    Kawasaki-shi Kanagawa 210-0865 (JP)

(74) Representative: dompatent von Kreisler Selting Werner - Partnerschaft von Patent- und Rechtsanwälten mbB 
Deichmannhaus am Dom Bahnhofsvorplatz 1
50667 Köln
50667 Köln (DE)


(56) References cited: : 
WO-A1-01/00225
WO-A2-2008/039267
JP-A- 2008 037 831
WO-A2-2008/039267
JP-A- 2005 145 959
US-A1- 2008 032 921
   
  • A. T. HEINY ET AL: "Evolutionarily Conserved Protein Sequences of Influenza A Viruses, Avian and Human, as Vaccine Targets", PLOS ONE, vol. 2, no. 11, E1190, 21 November 2007 (2007-11-21), pages 1-14, XP055002101, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0001190 -& A. T. HEINY ET AL: "Supporting Information- Table S2: Evolutionarily Conserved Protein Sequences of Influenza A Viruses, Avian and Human, as Vaccine Targets", PLOS ONE , 21 November 2007 (2007-11-21), XP002691001, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0001190.s002 Retrieved from the Internet: URL:http://www.plosone.org/article/fetchSi ngleRepresentation.action?uri=info:doi/10. 1371/journal.pone.0001190.s002 [retrieved on 2013-01-25]
  • NAGATA ET AL: "Peptides coupled to the surface of a kind of liposome protect infection of influenza viruses", VACCINE, ELSEVIER LTD, GB, vol. 25, no. 26, 1 June 2007 (2007-06-01), pages 4914-4921, XP022101827, ISSN: 0264-410X, DOI: 10.1016/J.VACCINE.2007.04.010
  • MAIKO TANEICHI ET AL: "Antigen Chemically Coupled to the Surface of Liposomes Are Cross-Presented to CD8+ T Cells and Induce Potent Antitumor Immunity", THE JOURNAL OF IMMUNOLOGY, THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, vol. 177, no. 4, 1 January 2006 (2006-01-01), pages 2324-2330, XP008148717, ISSN: 0022-1767
  • BEDNAREK ET AL: "The minimum peptide epitope from the influenza virus matrix protein. Extra and intracellular loading of HLA-A2.", THE JOURNAL OF IMMUNOLOGY, vol. 147, no. 12, 1 December 1991 (1991-12-01), pages 4047-4053, XP055050596, ISSN: 0022-1767
  • RIMMELZWAAN ET AL: "Influenza virus-specific cytotoxic T lymphocytes: a correlate of protection and a basis for vaccine development", CURRENT OPINION IN BIOTECHNOLOGY, LONDON, GB, vol. 18, no. 6, 4 January 2008 (2008-01-04), pages 529-536, XP022409620, ISSN: 0958-1669, DOI: 10.1016/J.COPBIO.2007.11.002
  • TETSUYA UCHIDA ET AL.: 'Banno Influenza Vaccine Jitsugen e Tsunagaru CTL Yudogata Liposome Vaccine no Kaihatsu' BIO INDUSTRY vol. 25, no. 11, 12 November 2008, pages 95 - 103, XP008164379
  • TETSUYA UCHIDA ET AL.: 'Liposome Hyomen Ketsugo Kogen o Mochiita Vaccine Sosei' JAPANESE JOURNAL OF CLINICAL MEDICINE vol. 66, no. 10, 01 October 2008, pages 1894 - 1902, XP008164339
  • P. C. DOHERTY ET AL: 'Cytotoxic T-cell responses in mice infected with influenza and vaccinia viruses vary in magnitude with H-2 genotype' THE JOURNAL OF EXPERIMENTAL MEDICINE vol. 148, no. 2, 01 August 1978, US, pages 534 - 543, XP055349309 DOI: 10.1084/jem.148.2.534 ISSN: 0022-1007
  • ROGIER BODEWES|JOOST H. C. M. KREIJTZ|MARINE. L. B. HILLAIRE|MARTINA M. GEELHOED-MIERAS|RON A. M. FOUCHIER|ALBERT D. M. E. OSTERHA: 'Microbiology Society Journals | Vaccination with whole inactivated virus vaccine affects the induction of heterosubtypic immunity against influenza virus A/H5N1 and immunodominance of virus-specific CD8+ T-cell responses in mice', [Online] 01 January 2010, XP055349314 Retrieved from the Internet: <URL:http://jgv.microbiologyresearch.org/co ntent/journal/jgv/10.1099/vir.0.020784-0#ta b2> [retrieved on 2017-02-24]
  • R A LAMB ET AL: 'Synthesis of influenza virus polypeptides in cells resistant to alpha-amanitin: evidence for the involvement of cellular RNA polymerase II in virus replication' JOURNAL OF VIROLOGY, [Online] 01 September 1977, UNITED STATES, pages 816 - 819, XP055349333 Retrieved from the Internet: <URL:http://jvi.asm.org/content/23/3/816.fu ll.pdf#page=1&view=FitH> [retrieved on 2017-00-00]
   
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