(19)

(11)

EP 2 370 003 A2

(12)

(88) Date of publication A3: 14.10.2010 (43) Date of publication: 05.10.2011 Bulletin 2011/40 (21) Application number: 09831063.4 (22) Date of filing: 02.12.2009

(51) International Patent Classification (IPC):  A61B 17/04(2006.01) A61B 17/08(2006.01) A61B 17/12(2006.01) A61F 2/02(2006.01) (86) International application number: PCT/US2009/066433 (87) International publication number: WO 2010/065654 (10.06.2010 Gazette 2010/23)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 05.12.2008 US 328979 28.05.2009 US 474254 (71) Applicant: Onciomed, Inc. Irvine, CA 92602 (US)	(72) Inventor: NIHALANI, Raj Irvine California 92602 (US) (74) Representative: Viering, Jentschura & Partner  Grillparzerstrasse 14 81675 München 81675 München (DE)