(19)
(11) EP 2 389 205 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
26.05.2021 Bulletin 2021/21

(45) Mention of the grant of the patent:
03.02.2021 Bulletin 2021/05

(21) Application number: 09832666.3

(22) Date of filing: 13.12.2009
(51) International Patent Classification (IPC): 
A61L 27/54(2006.01)
A61F 2/28(2006.01)
A61F 2/46(2006.01)
A61K 35/32(2015.01)
A61L 27/36(2006.01)
A61P 19/00(2006.01)
(86) International application number:
PCT/US2009/067799
(87) International publication number:
WO 2010/068939 (17.06.2010 Gazette 2010/24)

(54)

METHOD OF MAKING OSTEOINDUCTIVE BONE IMPLANT

VERFAHREN ZUR HERSTELLUNG VON OSTEOINDUKTIVEN KNOCHENIMPLANTATEN

METHODE DE FABRICATION DE GREFFONS OSSEUX OSTEOINDUCTIFS


(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

(30) Priority: 13.12.2008 US 201612 P
07.09.2009 US 240283 P

(43) Date of publication of application:
30.11.2011 Bulletin 2011/48

(73) Proprietor: Bioventus, LLC
Durham, NC 27703 (US)

(72) Inventor:
  • GOVIL, Amit, Prakash
    Irvine CA 92618 (US)

(74) Representative: REHBERG HÜPPE + PARTNER 
Patentanwälte PartG mbB Robert-Gernhardt-Platz 1
37073 Göttingen
37073 Göttingen (DE)


(56) References cited: : 
WO-A1-01/00792
WO-A2-03/051240
US-A1- 5 236 456
US-A1- 2007 154 563
US-B1- 6 189 537
WO-A1-2008/150508
KR-B1- 100 754 814
US-A1- 2001 020 188
US-A1- 2008 262 633
   
  • TZIAFAS D ET AL: "Inductive influences of demineralized dentin and bone matrix on pulp cells: an approach of secondary dentinogenesis", JOURNAL OF DENTAL RESEARCH, INTERNATIONAL ASSOCIATION FOR DENTAL RESEARCH, US, vol. 69, no. 1, 1 January 1990 (1990-01-01), pages 75-81, XP002501927, ISSN: 0022-0345, DOI: 10.2172/6776591
  • DA WAHL, JT CZERNUSZKA: 'Collagen-Hydroxyapatite Composites for Hard Tissue Repair' EUROPEAN CELLS AND MATERIALS vol. 11, 2006, pages 43 - 56, XP008153529
  • MARTIN D. KIRK, ARNOLD J. KAHN: 'Extracellular matrix synthesized by clonal osteogenic cells is osteoinductive in vivo and in vitro: Role of transforming growth factor- beta1 in osteoblast cell-matrix interaction' JOURNAL OF BONE AND MINERAL RESERCH vol. 10, no. 8, 1995, pages 1203 - 1208, XP008153516
  • PRAFULLA RAVAL, HOWARD H. T. HSU, H. CLARKE ANDERSON: 'Osteoinductive ability of confluent Saos-2 cells correlates with enhanced expression of bone morphogenetic proteins' JOURNAL OF ORTHOPAEDIC RESEARCH vol. 14, no. 4, July 1996, pages 605 - 610, XP008153533
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).