(19)

(11)

EP 2 393 498 A1

(12)

(43) Date of publication: 14.12.2011 Bulletin 2011/50 (21) Application number: 10706706.8 (22) Date of filing: 05.02.2010

(51) International Patent Classification (IPC):  A61K 31/713(2006.01) G01N 33/50(2006.01) A61P 35/00(2006.01) C07K 16/30(2006.01) C12N 15/113(2010.01) (86) International application number: PCT/GB2010/000204 (87) International publication number: WO 2010/089559 (12.08.2010 Gazette 2010/32)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 05.02.2009 GB 0901837 (71) Applicant: Cizzle Biotechnology Limited Heslington, York YO10 5DG (GB)	(72) Inventor: COVERLEY, Dawn Heslington, York YO10 5DG (GB) (74) Representative: O'Brien, Simon Warwick  D Young & Co LLP 120 Holborn London EC1N 2DY London EC1N 2DY (GB)