(19)

(11)

EP 2 396 365 A2

(12)

(88) Date of publication A3: 25.11.2010 (43) Date of publication: 21.12.2011 Bulletin 2011/51 (21) Application number: 10741516.8 (22) Date of filing: 11.02.2010

(51) International Patent Classification (IPC):  C08G 69/48(2006.01) A61K 31/7105(2006.01) A61K 9/16(2006.01) C08L 101/16(2006.01) A61K 48/00(2006.01) A61K 47/48(2006.01) (86) International application number: PCT/US2010/000390 (87) International publication number: WO 2010/093452 (19.08.2010 Gazette 2010/33)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 11.02.2009 US 207392 P (71) Applicant: UNIVERSITY OF HOUSTON Houston, TX 77204-2015 (US)	(72) Inventor: BIKRAM, Malavosklish Spring TX 77379 (US) (74) Representative: McQueen, Andrew Peter  Stevens, Hewlett & Perkins 1 St. Augustine's Place Bristol BS1 4UD Bristol BS1 4UD (GB)