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(11)

EP 2 398 323 A1

(12)

(43) Date of publication: 28.12.2011 Bulletin 2011/52 (21) Application number: 09841603.5 (22) Date of filing: 19.02.2009

(51) International Patent Classification (IPC):  A01N 43/50(2006.01) A61K 31/415(2006.01) (86) International application number: PCT/US2009/001054 (87) International publication number: WO 2010/104488 (16.09.2010 Gazette 2010/37)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR (71) Applicant: University of Connecticut Farmington, CT 06030-6207 (US)	(72) Inventors: MAKRIYANNIS, Alexandros Watertown MA 02472 (US) VEMURI, Venkata, Kiran Boston MA 02115 (US) THOTAPALLY, Rajesh Adyar Chennai 600020 (IN) OLSZEWSKA, Teresa PL-80-952 Gdansk (PL) (74) Representative: Beacham, Annabel Rose  Dehns St Bride's House 10 Salisbury Square London EC4Y 8JD London EC4Y 8JD (GB)