(19)

(11)

EP 2 398 462 A1

(12)

(43) Date of publication: 28.12.2011 Bulletin 2011/52 (21) Application number: 10744110.7 (22) Date of filing: 26.01.2010

(51) International Patent Classification (IPC):  A61K 9/12(2006.01) (86) International application number: PCT/US2010/022071 (87) International publication number: WO 2010/096242 (26.08.2010 Gazette 2010/34)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 18.02.2009 US 153556 P (71) Applicant: Aradigm Corporation Hayward, CA 94545 (US)	(72) Inventors: CIPOLLA, David C. San Ramon California 94583 (US) GONDA, Igor San Francisco California 94107 (US) (74) Representative: Duxbury, Stephen et al Arnold & Siedsma Pettenkoferstrasse 37 80336 München 80336 München (DE)