(19)
(11) EP 2 398 495 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
17.06.2015 Bulletin 2015/25

(45) Mention of the grant of the patent:
29.04.2015 Bulletin 2015/18

(21) Application number: 09799683.9

(22) Date of filing: 16.12.2009
(51) International Patent Classification (IPC): 
A61K 38/48(2006.01)
(86) International application number:
PCT/GB2009/002892
(87) International publication number:
WO 2010/094905 (26.08.2010 Gazette 2010/34)

(54)

MODIFIED NON-CYTOTOXIC PROTEASES

MODIFIZIERTE NICHT-ZYTOTOXISCHE PROTEASEN

PROTÉASES NON CYTOTOXIQUES MODIFIÉES

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

(30) Priority: 23.02.2009 GB 0903006

(43) Date of publication of application:
28.12.2011 Bulletin 2011/52

(73) Proprietor: Ipsen Bioinnovation Limited
Abingdon Oxfordshire OX14 3YS (GB)

(72) Inventors:
  • CHADDOCK, John, Andrew
    Abingdon Oxfordshire OX14 3YS (GB)
  • FOSTER, Keith, Alan
    Abingdon Oxfordshire OX14 3YS (GB)

(74) Representative: MacLean, Martin Robert et al
Mathys & Squire LLP
The Shard 32 London Bridge Street London SE1 9SG
The Shard 32 London Bridge Street London SE1 9SG (GB)


(56) References cited: : 
WO-A2-02/44199
WO-A2-2009/150470
 WO-A2-2006/059113
US-A1- 2008 038 274
   
  • CHADDOCK J A ET AL: "Clostridial neurotoxins: structure-function led design of new therapeutics" CMLS CELLULAR AND MOLECULAR LIFE SCIENCES, BIRKHÄUSER-VERLAG, BA LNKD- DOI:10.1007/S00018-005-5505-5, vol. 63, no. 5, 1 March 2006 (2006-03-01), pages 540-551, XP019201042 ISSN: 1420-9071 cited in the application
  • FOSTER K A ET AL: "Re-engineering the target specificity of Clostridial neurotoxins - a route to novel therapeutics" NEUROTOXICITY RESEARCH, HARWOOD ACADEMIC PUBLISHERS, LAUSANNE, CH, vol. 9, no. 2-3, 1 April 2006 (2006-04-01) , pages 101-107, XP009089826 ISSN: 1029-8428
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).