(19)

(11)

EP 2 403 839 A2

(12)

(88) Date of publication A3: 31.03.2011 (43) Date of publication: 11.01.2012 Bulletin 2012/02 (21) Application number: 10749395.9 (22) Date of filing: 05.03.2010

(51) International Patent Classification (IPC):  C07D 265/06(2006.01) C07D 403/04(2006.01) C07D 473/02(2006.01) (86) International application number: PCT/US2010/026372 (87) International publication number: WO 2010/102212 (10.09.2010 Gazette 2010/36)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 06.03.2009 US 158306 P 27.03.2009 US 164282 P (71) Applicant: The University of North Carolina At Chapel Hill Chapel Hill, NC 27599-4105 (US)	(72) Inventor: LONGO, Frank, M. Menlo Park, CA 94025 (US) (74) Representative: Behnisch, Werner  Reinhard, Skuhra, Weise & Partner GbR Patent- und Rechtsanwälte Friedrichstrasse 31 80801 München 80801 München (DE)