(19)

(11)

EP 2 408 448 A2

(12)

(88) Date of publication A3: 10.03.2011 (43) Date of publication: 25.01.2012 Bulletin 2012/04 (21) Application number: 10753957.9 (22) Date of filing: 16.03.2010

(51) International Patent Classification (IPC):  A61K 31/416(2006.01) A61P 31/00(2006.01) A61P 31/12(2006.01) (86) International application number: PCT/US2010/027405 (87) International publication number: WO 2010/107742 (23.09.2010 Gazette 2010/38)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 18.03.2009 US 383030 18.03.2009 US 383071 (71) Applicants: The Board Of Trustees Of The University Of the Leland Stanford Junior University Palo Alto, CA 94306-1106 (US) Eiger Biopharmaceuticals, Inc. Palo Alto, CA 94303 (US)	(72) Inventors: CHOONG, Ingrid, C. Palo Alto, CA 94303 (US) GLENN, Jeffrey, S. Palo Alto CA 94304 (US) YANG, Wenjin Foster City CA 94404 (US) (74) Representative: Larcher, Dominique  Cabinet Vidon, 16 B, rue Jouanet, BP 90333 Technopole Atalante 35703 Rennes Cedex 7 35703 Rennes Cedex 7 (FR)