(19)

(11)

EP 2 409 142 A2

(12)

(88) Date of publication A3: 13.01.2011 (43) Date of publication: 25.01.2012 Bulletin 2012/04 (21) Application number: 10754075.9 (22) Date of filing: 17.03.2010

(51) International Patent Classification (IPC):  G01N 27/26(2006.01) G01N 27/416(2006.01) (86) International application number: PCT/US2010/027697 (87) International publication number: WO 2010/107941 (23.09.2010 Gazette 2010/38)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 19.03.2009 US 161671 P 16.03.2010 US 724583 (71) Applicant: Edwards Lifesciences Corporation Irvine, CA 92614 (US)	(72) Inventors: OVIATT, Henry, Jr. Irvine CA 92614 (US) PETISCE, James, R. Irvine CA 92614 (US) MOONEY, Charles Irvine CA 92614 (US) (74) Representative: Eisenführ, Speiser & Partner  Postfach 31 02 60 80102 München 80102 München (DE)