(19)

(11)

EP 2 411 503 A1

(12)

(43) Date of publication: 01.02.2012 Bulletin 2012/05 (21) Application number: 10715098.9 (22) Date of filing: 25.03.2010

(51) International Patent Classification (IPC):  C12N 1/20(2006.01) C07K 14/205(2006.01) C12N 1/36(2006.01) A61K 39/106(2006.01) (86) International application number: PCT/EP2010/001884 (87) International publication number: WO 2010/108682 (30.09.2010 Gazette 2010/39)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 27.03.2009 EP 09004445 (71) Applicant: Eidgenössische Technische Hochschule Zürich 8092 Zürich (CH)	(72) Inventors: ILG, Karin CH-8049 Zürich (CH) AEBI, Markus CH-5430 Wettingen (CH) AHUJA, Umesh Los Angeles, CA 90066 (US) AMBER, Saba Goleta, CA 90117 (US) SCHWARZ, Flavio CH-8050 Zürich (CH) (74) Representative: Kasche, André et al Ritscher & Partner AG Resirain 1 8125 Zollikerberg 8125 Zollikerberg (CH)