| (84) |
Designated Contracting States: |
|
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO
PL PT RO SE SI SK SM TR |
| (30) |
Priority: |
31.03.2009 US 202732 P
|
| (43) |
Date of publication of application: |
|
08.02.2012 Bulletin 2012/06 |
| (73) |
Proprietor: Centre Hospitalier Universitaire Vaudois |
|
1011 Lausanne (CH) |
|
| (72) |
Inventors: |
|
- BENHATTAR, Jean
CH-1009 Pully (CH)
- GUILLERET, Isabelle
CH-1110 Morges (CH)
|
| (74) |
Representative: KATZAROV S.A. |
|
European Patent Attorneys
19, rue des Epinettes
1227 Genève
1227 Genève (CH) |
| (56) |
References cited: :
EP-A1- 1 130 113
WO-A2-01/92579
|
WO-A1-2007/025594
US-A1- 2007 092 883
|
|
| |
|
|
- NYGREN ANDERS O H ET AL: "Methylation-specific MLPA (MS-MLPA): simultaneous detection
of CpG methylation and copy number changes of up to 40 sequences" NUCLEIC ACIDS RESEARCH,
vol. 33, no. 14, 2005, XP002596755 ISSN: 0305-1048
- JEUKEN JUDITH WM ET AL: "MS-MLPA: an attractive alternative laboratory assay for robust,
reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas"
LABORATORY INVESTIGATION, vol. 87, no. 10, October 2007 (2007-10), pages 1055-1065,
XP002596756 ISSN: 0023-6837
- SCHOUTEN J P ET AL: "Relative quantification of 40 nucleic acid sequences by multiplex
ligation-dependent probe amplification" NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY
PRESS, SURREY, GB LNKD- DOI:10.1093/NAR/GNF056, vol. 30, no. 12, 15 June 2002 (2002-06-15)
, pages 1-13, XP002362868 ISSN: 0305-1048
|
|
