TRICYCLIC CONDENSED HETEROCYCLIC COMPOUND, METHOD FOR PRODUCING SAME, AND USE THEREOF

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EP 2 415 768 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	24.06.2015 Bulletin 2015/26

(45)	Mention of the grant of the patent:
	29.04.2015 Bulletin 2015/18

(21)	Application number: 10758499.7

(22)	Date of filing: 24.03.2010

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International Patent Classification (IPC):

C07D 307/77^(2006.01)
A61K 35/74^(2015.01)
C12P 15/00^(2006.01)

A61K 31/343^(2006.01)
A61P 35/00^(2006.01)
C12P 17/04^(2006.01)

(86)	International application number:
	PCT/JP2010/055111

(87)	International publication number:
	WO 2010/113725 (07.10.2010 Gazette 2010/40)

(54)	TRICYCLIC CONDENSED HETEROCYCLIC COMPOUND, METHOD FOR PRODUCING SAME, AND USE THEREOF TRICYCLISCHE KONDENSIERTE HETEROCYCLISCHE VERBINDUNG, HERSTELLUNGSVERFAHREN DAFÜR UND VERWENDUNG DAVON COMPOSÉ HÉTÉROCYCLIQUE CONDENSÉ TRICYCLIQUE, SON PROCÉDÉ DE PRODUCTION ET SON UTILISATION

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

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Priority:

30.03.2009 JP 2009081345

(43)	Date of publication of application:
	08.02.2012 Bulletin 2012/06

(73)	Proprietor: Nippon Suisan Kaisha, Ltd.
	Minato-ku Tokyo 105-8676 (JP)

(72)	Inventors:
	SATO, Seizo Hachioji-shi Tokyo 192-0991 (JP) IWATA, Fumie Hachioji-shi Tokyo 192-0991 (JP) YAMADA, Shoichi Hachioji-shi Tokyo 192-0991 (JP) TAKEO,Jiro Hachioji-shi Tokyo 192-0991 (JP) ABE, Akihisa Hachioji-shi Tokyo 192-0991 (JP) KAWAHARA, Hiroyuki Hachioji-shi Tokyo 192-0991 (JP)

(74)	Representative: Vossius & Partner Patentanwälte Rechtsanwälte mbB
	Siebertstrasse 3 81675 München 81675 München (DE)

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References cited: :

WO-A1-2008/140150
JP-T- 2005 517 710

JP-T- 2003 509 508

'Dai 51 Kai Symposium on the Chemistry of Natural Products, Symposium Papers, 01 September 2009 (01.09.2009)', article FUMIE IWATA ET AL.: 'Idenshi Sodosei o Kagi to shita Kaiyo Kisho Hosenkin ga Sansei suru Shinki Seitai Kino Bunshi', pages 515 - 520
SATO S. ET AL.: 'Indoxamycins A-F. Cytotoxic tricycklic polypropionates from a marine- derived actinomycete' J. ORG. CHEM. vol. 74, 02 July 2009, pages 5502 - 5509
BUCHANAN O.G. ET AL.: 'Sporolides A and B: Structurally unprecedented halogenated macrolides from the marine actinomycete Salinispora tropica' ORG. LETT. vol. 7, no. 13, 2005, pages 2731 - 2734
HUGHES C.C. ET AL.: 'The marinopyrroles, antibiotics of an unprecedented structure class from a marine Streptomyces sp' ORG. LETT. vol. 10, no. 4, 2008, pages 629 - 631
KWON H.C. ET AL.: 'Marinomycins A-D, antitumor-antibiotics of a new structure class from a marine actinomycete of the recently discovered genus "marinispora"' J. AM. CHEM. SOC. vol. 128, 2006, pages 1622 - 1632
SEDAKOVA L.A. ET AL.: 'Antitumor and toxic effects of amotin' EKSPERIMENTAL'NAYA ONKOLOGIYA vol. 9, no. 5, 1987, pages 76 - 77

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).