(19)
(11) EP 2 416 806 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
15.03.2017 Bulletin 2017/11

(45) Mention of the grant of the patent:
14.12.2016 Bulletin 2016/50

(21) Application number: 09786466.4

(22) Date of filing: 10.04.2009
(51) International Patent Classification (IPC): 
A61K 49/00(2006.01)
A61K 49/08(2006.01)
A61K 51/04(2006.01)
A61K 49/12(2006.01)
A61K 51/06(2006.01)
A61K 103/10(2006.01)
A61K 49/04(2006.01)
A61K 49/22(2006.01)
A61K 51/00(2006.01)
A61K 49/18(2006.01)
B82Y 5/00(2011.01)
G01N 33/60(2006.01)
(86) International application number:
PCT/IB2009/052791
(87) International publication number:
WO 2010/116209 (14.10.2010 Gazette 2010/41)

(54)

FUCOIDANS AS LIGANDS FOR THE DIAGNOSIS OF DEGENERATIVE PATHOLOGIES

FUCOIDANE ALS LIGANDEN ZUR DIAGNOSE VON DEGENERATIVEN PATHOLOGIEN

FUCOÏDANES EN TANT QUE LIGANDS POUR LE DIAGNOSTIC DE PATHOLOGIES DÉGÉNÉRATIVES


(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

(43) Date of publication of application:
15.02.2012 Bulletin 2012/07

(60) Divisional application:
16191071.6

(73) Proprietors:
  • INSERM (Institut National de la Santé et de la Recherche Médicale)
    75654 Paris Cedex 13 (FR)
  • Université Paris 13
    93430 Villetaneuse (FR)

(72) Inventors:
  • MICHEL, Jean-Baptiste
    F-75877 Paris Cedex 18 (FR)
  • LETOURNEUR, Didier
    F-75877 Paris Cedex 18 (FR)
  • CHAUBET, Frédéric
    F-75877 Paris Cedex 18 (FR)
  • BACHELET, Laure
    F-75877 Paris Cedex 18 (FR)
  • ROUZET, François
    F-75877 Paris Cedex 18 (FR)
  • MEULEMANS, Alain
    F-75877 Paris Cedex 18 (FR)

(74) Representative: Cabinet Plasseraud 
66 rue de la Chaussée d'Antin
75440 Paris Cedex 09
75440 Paris Cedex 09 (FR)


(56) References cited: : 
   
  • HARIRI G ET AL: "Radiation-Guided P-Selectin Antibody Targeted to Lung Cancer" ANNALS OF BIOMEDICAL ENGINEERING, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NE, vol. 36, no. 5, 14 February 2008 (2008-02-14), pages 821-830, XP019598332 ISSN: 1573-9686
  • GRATZ S ET AL: "99MTC-E-SELECTIN BINDING PEPTIDE FOR IMAGING ACUTE OSTEOMYELITIS IN A NOVEL RAT MODEL" NUCLEAR MEDICINE COMMUNICATIONS, LIPPINCOTT WILLIAMS AND WILKINS, XX, vol. 22, no. 9, 1 September 2001 (2001-09-01), pages 1003-1013, XP009076103 ISSN: 0143-3636
  • BACHELET L ET AL: "Affinity of low molecular weight fucoidan for P-selectin triggers its binding to activated human platelets" BIOCHIMICA ET BIOPHYSICA ACTA - GENERAL SUBJECTS, ELSEVIER SCIENCE PUBLISHERS, NL, vol. 1790, no. 2, 1 February 2009 (2009-02-01), pages 141-146, XP025868654 ISSN: 0304-4165 [retrieved on 2008-11-05]
  • YOSHIDA T ET AL: "A LIQUID-PHASE BINDING ANALYSIS FOR L-SELECTIN. A STRONG DEPENDENCY ON HIGHLY CLUSTERED SULFATE GROUPS" EUROPEAN JOURNAL OF BIOCHEMISTRY, BLACKWELL PUBLISHING, BERLIN, DE, vol. 222, no. 2, 1 January 1994 (1994-01-01), pages 703-709, XP000614583 ISSN: 0014-2956
  • VASS J A ET AL: "Biotinylated L-selectin ligand analogs as cytochemical probes in cytospin preparations" FOLIA HISTOCHEMICA ET CYTOBIOLOGICA 1995 PL, vol. 33, no. 1, 1995, pages 39-41, XP008114481 ISSN: 0015-5586
   
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