(19)

(11)

EP 2 421 517 A2

(12)

(88) Date of publication A3: 17.03.2011 (43) Date of publication: 29.02.2012 Bulletin 2012/09 (21) Application number: 10767428.5 (22) Date of filing: 21.04.2010

(51) International Patent Classification (IPC):  A61K 9/52(2006.01) A61K 9/51(2006.01) A61M 35/00(2006.01) A61K 9/50(2006.01) A61K 47/30(2006.01) (86) International application number: PCT/US2010/001191 (87) International publication number: WO 2010/123563 (28.10.2010 Gazette 2010/43)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 23.04.2009 US 386853 23.04.2009 US 214452 P 25.11.2009 US 592536 (71) Applicant: Sustained Nano Systems Llc Great Neck, NY 11023 (US)	(72) Inventors: BARRY, Libin Great Neck, NY 11023 (US) LIEBMANN, Jeffrey, M. Great Neck, NY 11023 (US) CHEN, Weiliam MT Sinai, NY 11766 (US) (74) Representative: Bottero, Carlo et al Barzano' & Zanardo Milano S.p.A. Via Borgonuovo, 10 20121 Milano 20121 Milano (IT)