(19)

(11)

EP 2 432 497 A1

(12)

(43) Date of publication: 28.03.2012 Bulletin 2012/13 (21) Application number: 10732461.8 (22) Date of filing: 18.05.2010

(51) International Patent Classification (IPC):  A61K 38/46(2006.01) (86) International application number: PCT/NL2010/050294 (87) International publication number: WO 2010/134806 (25.11.2010 Gazette 2010/47)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 18.05.2009 US 179253 P (71) Applicants: Amsterdam Molecular Therapeutics (AMT) IP B.V. 1105 BA Amsterdam (NL) De Wal, Janneke 1105 BA Amsterdam (NL) Gaudet, Daniel Chicoutimi, Québec G7H 5H6 (CA)	(72) Inventors: DE WAL, Janneke NL-1105 BA Amsterdam (NL) GAUDET, Daniel Chicoutimi, Québec G7H 5H6 (CA) (74) Representative: Pallard, Caroline Chantal Patricia  Nederlandsch Octrooibureau J.W. Frisolaan 13 2517 JS Den Haag 2517 JS Den Haag (NL)