| (84) |
Designated Contracting States: |
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AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL
NO PL PT RO SE SI SK SM TR |
| (30) |
Priority: |
05.06.2009 US 184658 P
|
| (43) |
Date of publication of application: |
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11.04.2012 Bulletin 2012/15 |
| (73) |
Proprietor: Cavion, Inc. |
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Charlottesville, VA 22902 (US) |
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| (72) |
Inventors: |
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- KROUSE, Andrew J.
Charlottesville,
Virginia 22911 (US)
- GRAY, Lloyd S.
Louisa,
Virginia 23093 (US)
- MACDONALD, Timothy
Charlottesville,
Virginia 22902 (US)
- LINDEN, Joel
Charlottesville,
Virginia 22901 (US)
|
| (74) |
Representative: Hoffmann Eitle |
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Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München
81925 München (DE) |
| (56) |
References cited: :
WO-A2-2006/023883
US-A1- 2008 194 669
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US-A1- 2006 003 020
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MACDONALD T L: "Design, synthesis, and biological evaluation of novel T-Type calcium
channel antagonists", BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 14, no. 14,
16 July 2004 (2004-07-16) , pages 3691-3695, XP002692339, DOI: 10.1016/j.bmcl.2004.05.011
- HAVERSTICK D M; HEADY T N; MACDONALD T L; GRAY L S: "Inhibition of human prostate
cancer proliferation in vitro and in a mouse model by a compound synthesized to block
Ca<2+> entry<1>", CANCER RESEARCH, vol. 60, 15 February 2000 (2000-02-15), pages 1002-1008,
XP002692338,
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122, no. 2, 15 January 2008, pages 444 - 451, XP055074821
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2006, pages 455 - 460, XP005853890
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