(19)
(11) EP 2 451 968 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
08.04.2015 Bulletin 2015/15

(45) Mention of the grant of the patent:
21.01.2015 Bulletin 2015/04

(21) Application number: 10725083.9

(22) Date of filing: 08.06.2010
(51) International Patent Classification (IPC): 
C12Q 1/68(2006.01)
(86) International application number:
PCT/EP2010/058022
(87) International publication number:
WO 2011/003690 (13.01.2011 Gazette 2011/02)

(54)

HIGHLY SENSITIVE RAPID ISOTHERMAL METHOD FOR THE DETECTION OF POINT MUTATIONS AND SNPS, A SET OF PRIMERS AND A KIT THEREFOR

Hochsensibles schnelles isothermisches Verfahren zur Detektion von Punktmutationen und SNPs

Procédé isothermique rapide et hautement sensible pour la détection de mutations ponctuelles et SNP

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

(30) Priority: 10.07.2009 EP 09165252

(43) Date of publication of application:
16.05.2012 Bulletin 2012/20

(73) Proprietor: Diasorin Ireland Limited
Co. Dublin (IE)

(72) Inventors:
  • ADLERSTEIN, Daniel
    I-20020 Arese (Milano) (IT)
  • AMICARELLI, Giulia
    27020 Travaco' Siccomario (Pavia) (IT)
  • MINNUCCI, Giulia
    I-20151 Milano (IT)

(74) Representative: Comoglio, Elena et al
Jacobacci & Partners S.p.A. Corso Emilia 8
10152 Torino
10152 Torino (IT)


(56) References cited: : 
EP-A2- 1 975 249
WO-A2-2007/011901
US-A1- 2007 218 464
 WO-A1-2009/049630
WO-A2-2009/073575
   
  • NAGAMINE K ET AL: "Accelerated reaction by loop-mediated isothermal amplification using loop primers." MOLECULAR AND CELLULAR PROBES JUN 2002, vol. 16, no. 3, June 2002 (2002-06), pages 223-229, XP002573824 ISSN: 0890-8508
  • MURUGESAN GURUNATHAN ET AL: "Identification of the JAK2 V617F mutation in chronic myeloproliferative disorders using FRET probes and melting curve analysis." AMERICAN JOURNAL OF CLINICAL PATHOLOGY APR 2006, vol. 125, no. 4, April 2006 (2006-04), pages 625-633, XP002568551 ISSN: 0002-9173
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).