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EP 2 454 269 A1

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(43) Date of publication: 23.05.2012 Bulletin 2012/21 (21) Application number: 10800125.6 (22) Date of filing: 15.07.2010

(51) International Patent Classification (IPC):  C07H 21/00(2006.01) C08L 89/00(2006.01) C12Q 1/68(2006.01) G01N 33/50(2006.01) (86) International application number: PCT/SG2010/000266 (87) International publication number: WO 2011/008173 (20.01.2011 Gazette 2011/03)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 15.07.2009 US 225881 P 22.07.2009 WO PCT/SG2009/000258 (71) Applicant: Agency for Science, Technology and Research Singapore 138632 (SG)

(72) Inventors: HEATH, James R. Singapore 138669 (SG) LEE, Su Seong Singapore 138669 (SG) LIM, Jaehong Singapore 138669 (SG) CHA, Junhoe Singapore 138669 (SG) TAN, Sylvia Singapore 138669 (SG) YEO, Shi Yun Singapore 138669 (SG) ANG, Yi Li Singapore 138669 (SG) ZHANG, Yiran Singapore 138669 (SG) (74) Representative: Clegg, Richard Ian et al Mewburn Ellis LLP 33 Gutter Lane London EC2V 8AS London EC2V 8AS (GB)