(19)

(11)

EP 2 454 277 A1

(12)

(43) Date of publication: 23.05.2012 Bulletin 2012/21 (21) Application number: 10736844.1 (22) Date of filing: 16.07.2010

(51) International Patent Classification (IPC):  C07K 14/415(2006.01) C12N 15/82(2006.01) (86) International application number: PCT/NL2010/050461 (87) International publication number: WO 2011/008096 (20.01.2011 Gazette 2011/03)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 16.07.2009 EP 09165714 (71) Applicant: Wageningen Universiteit 6701 BH Wageningen (NL)	(72) Inventors: GONÇALVES LEITE DE ASSUNÇAO, Ana DK-2200 Kbh N Copenhagen (DK) AARTS, Martinus Gerardus Maria NL-6706 AZ Wageningen (NL) (74) Representative: Jansen, Cornelis Marinus  VEREENIGDE Johan de Wittlaan 7 2517 JR Den Haag 2517 JR Den Haag (NL)